Chromatin – DNA fragments by sonication and immunoprecipitated
Regulatory mechanisms governing chromatin organization and function

Regulatory mechanisms governing chromatin organization and function

Zoe
Zoe

Nucleosomes, the fundamental constructions used to bundle genetic info into chromatin, are topic to a various array of chemical modifications. Numerous these marks function interplay hubs for a lot of nuclear proteins and supply essential structural options for protein recruitment. Dynamic deposition and elimination of chromatin modifications by regulatory proteins guarantee their right deposition to the genome, which is important for DNA replication, transcription, chromatin compaction, or DNA injury restore. The spatiotemporal regulation and upkeep of chromatin marks depends on coordinated actions of author, eraser, and reader enzymes and infrequently depends upon complicated multicomponent regulatory circuits. In recent times, the sphere has made huge advances in uncovering the mechanisms that regulate chromatin modifications.

 

Right here, we focus on well-established and rising ideas in chromatin biology starting from cooperativity and multivalent interactions to regulatory suggestions loops and elevated native focus of chromatin-modifying enzymes.  The Reworking Progress Issue-β (TGFβ) signaling pathway controls transcription by regulating enhancer exercise. How TGFβ-regulated enhancers are chosen and what chromatin adjustments are related to TGFβ-dependent enhancers regulation are nonetheless unclear. Right here we report that TGFβ therapy triggers quick and widespread improve in chromatin accessibility in about 80% of the enhancers of regular mouse mammary epithelial-gland cells, regardless of whether or not they’re activated, repressed or not regulated by TGFβ. This enhancer opening depends upon each the canonical and non-canonical TGFβ pathways. Most TGFβ-regulated genes are situated round enhancers regulated in the identical method, typically creating domains of a number of co-regulated genes that we time period TGFβ regulatory domains (TRD).

 

Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology

Utilizing Hello-C, promoter-capture Hello-C (pCHi-C), and different genome-wide approaches in skeletal muscle progenitors that inducibly categorical a grasp transcription issue, Pax7, we systematically characterize at high-resolution the spatio-temporal re-organization of compartments and promoter-anchored interactions as a consequence of myogenic dedication and differentiation. We determine key promoter-enhancer interplay motifs, particularly, cliques and networks, and interactions which might be depending on Pax7 binding. Remarkably, Pax7 binds to a majority of super-enhancers, and along with a cadre of interacting transcription elements, assembles feed-forward regulatory loops.
Throughout differentiation, epigenetic reminiscence and chronic looping are maintained at a subset of Pax7 enhancers within the absence of Pax7. We additionally determine and functionally validate a beforehand uncharacterized Pax7-bound enhancer hub that regulates the important myosin heavy chain cluster throughout skeletal muscle cell differentiation. Our research lay the groundwork for understanding the function of Pax7 in orchestrating adjustments within the three-dimensional chromatin conformation in muscle progenitors. Class I histone deacetylase complexes play important roles in lots of nuclear processes. While they comprise a standard catalytic subunit, they’ve various modes of motion decided by related elements within the distinct complexes.
The deacetylase module from the NuRD complicated comprises three protein domains that management the recruitment of chromatin to the deacetylase enzyme, HDAC1/2. Utilizing biochemical approaches and cryo-electron microscopy, we have now decided how three chromatin-binding domains (MTA1-BAH, MBD2/three and RBBP4/7) are assembled in relation to the core complicated in order to facilitate interplay of the complicated with the genome. We observe a placing association of the BAH domains suggesting a possible mechanism for binding to di-nucleosomes.
 Regulatory mechanisms governing chromatin organization and function
Regulatory mechanisms governing chromatin organization and function

The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein

Ssr4 is a yeast protein from Schizosaccharomyces pombe and is a necessary a part of the chromatin-remodelling [SWI/SNF and RSC (remodelling the structure of chromatin)] complexes present in S. pombe. These complexes (or their homologues) regulate gene expression in eukaryotic organisms, affecting a lot of genes each positively and negatively. The downstream results are seen in growth, and in people have implications for illness similar to most cancers. The chromatin construction is altered by modifying the DNA-histone contacts, thus opening up or closing down sections of DNA to particular transcription elements that regulate the transcription of genes. The Ssr4 sequence has little homology to different sequences within the Protein Knowledge Financial institution, so the construction was solved utilizing an iodine spinoff with SAD phasing.
The construction of the N-terminal area is an antiparallel β-sheet of seven strands with α-helices on one facet and random coil on the opposite. The construction is considerably completely different to deposited constructions and was used as a goal in the newest Important Evaluation of Methods for Protein Construction Prediction Rising proof means that chromodomain-helicase-DNA-binding (CHD) proteins are concerned in stem cell upkeep and differentiation through the coordination of chromatin construction and gene expression.

Chemical phosphorylation amidite, 5 g

62560 5 g
EUR 1711.2

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx135705
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx176210
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx176211
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx172170
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (Dyrk1a) Antibody

abx031012-400ul 400 ul
EUR 627.6

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (Dyrk1a) Antibody

abx031012-80l 80 µl
EUR 343.2

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

abx033472-400ul 400 ul
EUR 627.6

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

abx033472-80l 80 µl
EUR 343.2

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

abx033473-400ul 400 ul
EUR 627.6

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

abx033473-80l 80 µl
EUR 343.2

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx128317
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx329453
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

abx431220-200ul 200 ul
EUR 460.8

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Antibody

20-abx009320
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Rat phosphorylation AKT(p-AKT)ELISA Kit

YLA0398RA-48T 48T
EUR 465

Rat phosphorylation AKT(p-AKT)ELISA Kit

YLA0398RA-96T 96T
EUR 600

EnzyFluo™ ERK Phosphorylation Assay Kit

EERK-100 100
EUR 569
Description: For quantitative fluorescent immunoenzymatic assay of ERK1/2 phosphorylation status in cultured cells. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-based ELISA (FL360/450nm, 530/585nm). Samples: Cells. Species: Human, mouse, rat. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

Calcium-Binding Tyrosine Phosphorylation-Regulated Protein (CABYR) Antibody

abx231170-100ug 100 ug
EUR 610.8

Calcium-Binding Tyrosine Phosphorylation-Regulated Protein (CABYR) Antibody

20-abx148788
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Calcium-Binding Tyrosine Phosphorylation-Regulated Protein (CABYR) Antibody

20-abx111304
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Calcium-Binding Tyrosine Phosphorylation-Regulated Protein (CABYR) Antibody

abx340188-100ug 100 ug
EUR 469.2

Chemical Phosphorylation Reagent I (CPR I)

6001 1 g
EUR 558

EnzyFluo™ NFkB Phosphorylation Assay Kit

ENFKB-100 100
EUR 559
Description: For quantitative fluorescent immunoenzymatic assay of NFkB phosphorylation status in cultured cells. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: FL360/450nm, 530/585nm. Samples: Cells. Species: Human, mouse. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ AMPK Phosphorylation Assay Kit

EAMPK-100 100
EUR 559
Description: For quantitative fluorescent immunoenzymatic assay of AMPK phosphorylation status in cultured cells. Key Features: Sensitive. Can measure pAMPK modulation in as little as 500 cells/well. New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: FL360/450nm, 530/585nm. Samples: Cells. Species: Human, mouse, rat. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

Chemical Phosphorylation Reagent I (CPR I)

6001-1g 1 g
EUR 558
Description: This reagent can be used to create the 3'-phosphate by adding it as the first addition to the support.

Human phosphorylation AKT(p-AKT)ELISA Kit

YLA4295HU-48T 48T
EUR 435

Human phosphorylation AKT(p-AKT)ELISA Kit

YLA4295HU-96T 96T
EUR 562.5

Human Glycogen phosphorylation(GP)ELISA Kit

QY-E05461 96T
EUR 433.2

EnzyFluo™ Human SHP2 (Y542) Phosphorylation ELISA Kit

ESHP2-100 100
EUR 509
Description: For determination of SHP2(Y542) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human)

4-PAJ193Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A)

EnzyFluo™ Human/Mouse RPS6(S235/236) Phosphorylation ELISA

ERPS6-100 100
EUR 509
Description: For determination of RPS6(S235/236) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, rat and mouse. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), APC

4-PAJ193Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with APC.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), Cy3

4-PAJ193Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with Cy3.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), HRP

4-PAJ193Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with HRP.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), PE

4-PAJ193Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with PE.

EpiQuik In Situ Histone H3 Phosphorylation (Ser10) Assay Kit 

P-7001
  • EUR 876.06
  • EUR 577.50
  • 96 Assays
  • 96 Assays 

EnzyFluo™ Human/Mouse GSK3B(S9) Phosphorylation ELISA Kit

EGSK3B-100 100
EUR 509
Description: For determination of GSK3B(S9) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, rat and mouse. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ Human/Mouse RB(T821/826) Phosphorylation ELISA Kit

ERBT-100 100
EUR 509
Description: For determination of RB(T821/826) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, rat and mouse. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ Human/Mouse AKT1(S473) Phosphorylation ELISA Kit

EAKT1-100 100
EUR 509
Description: For determination of AKT1(S473) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, rat and mouse. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ Human/Mouse LKB1(S431) Phosphorylation ELISA Kit

ELKB1-100 100
EUR 509
Description: For determination of LKB1(S431) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, mouse, and rat. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ Human/Mouse 4EBP1(S65) Phosphorylation ELISA Kit

E4EBP-100 100
EUR 509
Description: For determination of 4EBP1(S65) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human (S65), mouse/rat (S64). Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

EnzyFluo™ Human/Mouse GSK3A(S21) Phosphorylation ELISA Kit

EGSK3A-100 100
EUR 509
Description: For determination of GSK3A(S21) phosphorylation status in whole cells and evaluation of pathway modulation by activators, inhibitors, siRNA etc. Key Features: New and improved. Total assay time reduced from the standard 21 hours to 6.5 hours (hands-on time 2.5 hrs). Simple and convenient. Cells are directly cultured in 96-well plates. No cell lysis necessary. Accurate and high-throughput. Protein phosphorylation is normalized to total cellular protein in the same well, greatly minimizing well-to-well variations. Can be readily automated as a high-throughput 96-well plate assay for thousands of samples per day. Method: Cell-Based ELISA (FL530/585 nm, 360/450 nm). Samples: Cells. Species: human, rat, mouse, and canine. Procedure: Assay takes Assay takes 6.5 hrs, hands-on time 2.5 hrs. Kit size: 100 tests.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), FITC

4-PAJ193Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with FITC.

Dog Phosphorylation of AMP activated protein kinase ELISA kit

E08P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation of AMP activated protein kinase ELISA kit

E08P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation of AMP activated protein kinase ELISA kit

E08P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation of AMP activated protein kinase ELISA kit

E02P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation of AMP activated protein kinase ELISA kit

E02P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation of AMP activated protein kinase ELISA kit

E02P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation of AMP activated protein kinase ELISA kit

E07P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation of AMP activated protein kinase ELISA kit

E07P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation of AMP activated protein kinase ELISA kit

E07P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation of AMP activated protein kinase ELISA kit

E06P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation of AMP activated protein kinase ELISA kit

E06P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation of AMP activated protein kinase ELISA kit

E06P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Dual specificity tyrosine- phosphorylation- regulated kin

ELI-27714Ra 96 Tests
EUR 1113.6

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), APC-Cy7

4-PAJ193Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with APC-Cy7.

Mouse Phosphorylation of AMP activated protein kinase ELISA kit

E03P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Phosphorylation of AMP activated protein kinase ELISA kit

E03P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Phosphorylation of AMP activated protein kinase ELISA kit

E03P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation of AMP activated protein kinase ELISA kit

E01P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation of AMP activated protein kinase ELISA kit

E01P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation of AMP activated protein kinase ELISA kit

E01P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cabyr ELISA Kit| Mouse Calcium-binding tyrosine phosphorylation

EF014364 96 Tests
EUR 826.8

Rabbit Phosphorylation of AMP activated protein kinase ELISA kit

E04P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Phosphorylation of AMP activated protein kinase ELISA kit

E04P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Phosphorylation of AMP activated protein kinase ELISA kit

E04P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation of AMP activated protein kinase ELISA kit

E09P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation of AMP activated protein kinase ELISA kit

E09P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation of AMP activated protein kinase ELISA kit

E09P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Fish phosphorylation of AMP-activated protein kinase ELISA Kit

QY-E150009 96T
EUR 573.6

Dog Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E08P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E08P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E08P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E02P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E02P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E02P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E07P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E07P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E07P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E06P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E06P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E06P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Phosphorylation of AMP activated protein kinase ELISA kit

E05P0187-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Phosphorylation of AMP activated protein kinase ELISA kit

E05P0187-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Phosphorylation of AMP activated protein kinase ELISA kit

E05P0187-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation of AMP activated protein kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E04P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E04P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E04P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E03P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E03P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E03P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E01P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E01P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E01P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E09P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E09P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E09P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Polyclonal Antibody (Human), Biotinylated

4-PAJ193Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A). This antibody is labeled with Biotin.

EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Colorimetric) 

P-7002
  • EUR 945.66
  • EUR 347.60
  • EUR 625.90
  • 96 Assays
  • 48 Assays
  • 96 Assays 

EpiQuik Global Histone H3 Phosphorylation (Ser10) Assay Kit (Fluorometric) 

P-7003
  • EUR 945.66
  • EUR 347.60
  • EUR 625.90
  • 96 Assays
  • 48 Assays
  • 96 Assays 

EpiQuik Global Histone H3 Phosphorylation (Ser28) Assay Kit (Colorimetric) 

P-7004
  • EUR 945.66
  • EUR 347.60
  • EUR 625.90
  • 96 Assays
  • 48 Assays
  • 96 Assays 

EpiQuik Global Histone H3 Phosphorylation (Ser28) Assay Kit (Fluorometric) 

P-7005
  • EUR 945.66
  • EUR 347.60
  • EUR 625.90
  • 96 Assays
  • 48 Assays
  • 96 Assays 

Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E05P0023-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E05P0023-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase ELISA kit

E05P0023-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Phosphorylation P38 Mitogen activated Protein Kinase in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation Extracellular signal Regulated Kinase 1/2 ELISA kit

E08P0049-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation Extracellular signal Regulated Kinase 1/2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation Extracellular signal Regulated Kinase 1/2 ELISA kit

E08P0049-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation Extracellular signal Regulated Kinase 1/2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Phosphorylation Extracellular signal Regulated Kinase 1/2 ELISA kit

E08P0049-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Phosphorylation Extracellular signal Regulated Kinase 1/2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Phosphorylation Extracellular signal Regulated Kinase 1/2 ELISA kit

E02P0049-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Phosphorylation Extracellular signal Regulated Kinase 1/2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Nonetheless, the molecular perform of some CHD proteins in stem cell regulation continues to be poorly understood. Herein, we present that Chd9 knockdown (KD) in mouse embryonic stem cells (ESCs) cultured in regular serum media, not in 2i-leukemia inhibitory issue (LIF) media, causes speedy cell proliferation.
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