Chromatin – DNA fragments by sonication and immunoprecipitated
chipready

DNA Fragmentation microbiome and its impact on sperm function a

The semen microbiome and its impact on sperm function and male fertility: A systematic review and meta-analysis

Background: Male factor is attributable in up to 50% of cases of infertility. In-vitro studies demonstrate that bacteria can negatively impact sperm function. The use of next-generation sequencing (NGS) techniques have provided a better understanding of the human microbiome, and dysbiosis has been reported to impact health. Evidence regarding the impact of the semen microbiome on sperm function and fertility remains conflicting.
Materials and methods: A systematic search was conducted in accordance with the Preferred Reporting Items for Reviews and Meta-analysis (PRISMA) statement. The databases MEDLINE, OVID and PubMed were searched to identify English language studies related to the identification of bacteria in the semen of infertile and fertile men, between 1992-2019. 55 observational studies were included, with 51299 subjects. We included studies identifying bacteria using NGS, culture or polymerase chain reaction (PCR).
Results: The semen microbiome (SM) was rich and diverse in both fertile and infertile men. Three NGS studies reported clustering of the seminal microbiome with a predominant species. Lactobacillus and Prevotella were dominant in respective clusters. Lactobacillus was associated with improvements in semen parameters.
  • Prevotella appeared to exert a negative effect on sperm quality. Bacteriospermia negatively impacted sperm concentration and progressive motility (PM), and DNA fragmentation index (DFI) (MD 3.518,95%CI 0.907 to 6.129, p=0.008). There was an increased prevalence of Ureaplasma urealyticum(UU) in infertile men(OR 2.25, 95% CI 1.47-3.46). UU negatively impacted concentration and morphology.
  • There was no difference in the prevalence of chlamydia trachomatis (CT) between fertile and infertile men and no significant impact on semen parameters. Enterococcus faecalis (EF) negatively impacted total motility and Mycoplasma hominis (MH) negatively impacted concentration, PM and morphology.

Sperm DNA Fragmentation: A New Guideline for Clinicians

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content.
Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA fragmentation (SDF), which affects both natural and assisted reproduction. Several clinical and environmental factors are known to negatively impact sperm DNA integrity.

An increasing number of reports emphasize the direct relationship between sperm DNA damage and male infertility. Currently, several assays are available to assess sperm DNA damage, however, routine assessment of SDF in clinical practice is not recommended by professional organizations.

This article provides an overview of SDF types, origin and comparative analysis of various SDF assays while primarily focusing on the clinical indications of SDF testing. Importantly, we report four clinical cases where SDF testing had played a significant role in improving fertility outcome. In light of these clinical case reports and recent scientific evidence, this review provides expert recommendations on SDF testing and examines the advantages and drawbacks of the clinical utility of SDF testing using Strength-Weaknesses-Opportunities-Threats (SWOT) analysis.
Keywords: Assisted reproductive techniques outcome; Clinical guidelines; Infertility, male; Oxidative stress; Sperm DNA fragmentation
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19 mm Diameter Solid Titanium Tip

0-120-0013 19 mm
EUR 570

25 mm Diameter Tapped Titanium Tip

0-120-0014 25 mm
EUR 682

25 mm Diameter Solid Titanium Tip

0-120-0015 25 mm
EUR 614

Flat Replaceable Tips 13 mm Diameter Flat Titanium Tip

0-120-0016 13 mm
EUR 86
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 19 mm Diameter Flat Titanium Tip

0-120-0017 19 mm
EUR 92
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 25 mm Diameter Flat Titanium Tip

0-120-0018 25 mm
EUR 100
Description: use with corresponding Tapped Tips and Tapped Extender Tips

Titanium Cup Tip, 250 ml

0-120-0019 250 ml
EUR 1377
Description: includes Interface Washers

Microtube Tray, 8 Position (for 250 ml Cup Tip)

0-120-0021 each
EUR 113
Description: includes Interface Washers

Continuous Flow Chamber

0-120-0026 each
EUR 774
Description: includes Interface Washers

Interface Washers 1.5” Diameter, 5/Pkg

0-120-003 1.5'' Diameter
EUR 31

13 mm Diameter Solid Titanium Extender Tip

0-120-0032 13 mm
EUR 301

13 mm Diameter Tapped Titanium Extender Tip

0-120-0033 13 mm
EUR 362

19 mm Diameter Solid Titanium Extender Tip

0-120-0034 19 mm
EUR 315

19 mm Diameter Tapped Titanium Extender Tip

0-120-0035 19 mm
EUR 375

25 mm Diameter Solid Titanium Extender Tip

0-120-0036 25 mm
EUR 328

25 mm Diameter Tapped Titanium Extender Tip

0-120-0037 25 mm
EUR 389

KoldPod, 1.5ml Micro Tube

0-120-0038 1.5 ml
EUR 152
Description: Thermo conductive tube pods

KoldPod, 15ml Conical Tube

0-120-0039 15 ml
EUR 275
Description: Thermo conductive tube pods

KoldPod, 50ml Conical Tube

0-120-0040 50 ml
EUR 290
Description: Thermo conductive tube pods

Model 150 V/T Ultrasonic Homogenizer

0-121-0002 210-240V/50-60Hz
EUR 2920
Description: Delivers up to 150 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample processing processing.

Model 300 V/T Ultrasonic Homogenizer

0-122-0002 210-240V/50-60Hz
EUR 3520
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample.

SONABOZ Sound Abating Chamber

0-125-0001 each
EUR 1020
Description: Reduces cavitational sound emitted during processing.

Model 3000 Ultrasonic Homogenizer

0-127-0002 210-240V/50-60Hz
EUR 4120
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip and includes an intergrated Sound Abating Chmaber to reduce cavitational sound emitted during processing. The Timer and Duty Cycle function increase preciosion in sample.

Model 3000MP Ultrasonic Homogenizer

0-128-0002 210-240V/50-60Hz
EUR 4720
Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip with preciosion control from a microprocessor and a graphical user interface displayed on a large (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted during processing.

OMNICON® Zone Reader, 210-240V/50-60Hz

0-131-0002 210-240V/50-60Hz
EUR 35200
Description: Designed to Perform multi-plate Assays on round 90/100mm Petri Dishes. The integrated LED illumination system provides transmitted light for brightfield and darkfield illumination of transparent media.

OMNI-Noculator Peni Cylinder Filler, 210-240V/50-60Hz

0-134-0002 210-240V/50-60Hz
EUR 32200
Description: A robotic liquid handling system designed to dispense Peni Cylinders and fill Peni Cylinders with the corresponding antibiotic liquid sample.

Peni Cylinder Dispenser with Manual Hopper

0-144-0002 each
EUR 5406
Description: Dispenser can be configured to dispense 4 or 6 Peni Cylinders onto a petri dish.

Peni Cylinder Dispenser with Motorized Hopper, 100-240V/50-60Hz

0-144-0003 100-240V/50-60Hz
EUR 6254
Description: The motorized hopper can be configured to dispense 4 or 6 Peni Cylinders onto a petri Dispenser can be disassembled for disinfection.

Stainless Steel Peni Cylinder with Flat Face

0-144-0005 6mm I.D. x 8mm O.D. x 10mm Long
EUR 399
Description: sold in packages of 100 pieces

Stainless Steel Peni Cylinder with Chamfered Face

0-144-0006 6mm I.D. x 8mm O.D. x 10mm Long
EUR 412
Description: sold in packages of 100 pieces

Custom development of ELISAs for other species or antibody isotypes not listed in the catalog. Custom testing of samples for IgG/IgM/IgA or total (IgG+IgM+IgA)

000-CUS Custom
EUR 602

Alpha-Bungarotoxin, CF®405S, 500 ug

00002 1UG
EUR 527
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-bungarotoxin, CF405s

00002 500uG
EUR 594
Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF®405S, 500 ug

00002-1 EA
EUR 527

Alpha-Bungarotoxin, CF®405S 100ug

00002-100ug 100uG
EUR 132
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

9-00003
  • Ask for price
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

00003-1 EA
EUR 527

Alpha-Bungarotoxin, CF®680R 100ug

9-00003
  • Ask for price
  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

9-00004
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

00004-1 EA
EUR 527

Alpha-Bungarotoxin, CF®640R 100ug

9-00004
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  • Ask for price
  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

9-00005
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

00005-1 EA
EUR 527

Alpha-Bungarotoxin CF®488A 100ug

9-00005
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

9-00006
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

00006-1 EA
EUR 527

Alpha-Bungarotoxin, CF®568 100ug

9-00006
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

9-00007
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

00007-1 EA
EUR 527

Alpha-Bungarotoxin CF®594 100ug

9-00007
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

9-00009
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

00009-1 EA
EUR 527

Alpha-Bungarotoxin, CF®633 100ug

9-00009
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  • 500uG
  • 100uG
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

SARS-CoV-2 Indicator Cell Line for RNA Replication - GFP Reporter only

0001-PP-001 1 cell line (can order x amount)
EUR 12000
Description: SARS-CoV-2 GFP reporter cell line using HEK293T (ACE2/TMPRSS2) cells

Alpha-Bungarotoxin, 1 mg

00010-1 1MG
EUR 193
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

00010-1-1 EA
EUR 193

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011 500uG
EUR 376
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-Alpha-Bungarotoxin, 500 ug

00011-1 EA
EUR 376

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012 500uG
EUR 394
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

00012-1 EA
EUR 394

Fluorescein-alpha-bungarotoxin, 10x50ug

00013 10ST
EUR 436
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-alpha-bungarotoxin, 10x50ug

00013-1 EA
EUR 436

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014 10ST
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

00014-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015 500uG
EUR 494
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

00015-1 EA
EUR 494

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016 10ST
EUR 560
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

00016-1 EA
EUR 560

Biotin-XX-A-Bungarotoxin, 500 ug

00017 500uG
EUR 455
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Biotin-XX-A-Bungarotoxin, 500 ug

00017-1 EA
EUR 455

Alpha-Bungarotoxin, CF®555, 500 ug

9-00018
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  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®555, 500 ug

00018-1 EA
EUR 527

Alpha-Bungarotoxin, CF®555 100ug

9-00018
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  • Ask for price
  • 500uG
  • 100ug
Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Acrylamide, Chemzymes Ultra Pure®

00019-100 100g
EUR 101.52
Description: 79-06-1

Acrylamide, Chemzymes Ultra Pure®

00019-500 500g
EUR 270
Description: 79-06-1

Biotin-cAMP, 1 mg

00020 1MG
EUR 298
Description: N/A

Biotin-cAMP, 1 mg

00020-1 20ST
EUR 298
Description: N/A

Biotin-cAMP, 50 ug

00020-1-1 EA
EUR 414

Biotin-cGMP, 1 mg

00021 1MG
EUR 331
Description: N/A

Biotin-cGMP, 1 mg

00021-1 20ST
EUR 331
Description: N/A

Biotin-cGMP, 20x50 ug

00021-1-1 EA
EUR 447

Cyanine 644-cAMP, 1 mg

00022 1MG
EUR 496
Description: N/A

Cyanine 644-cAMP, 1 mg

00022-1 20ST
EUR 496
Description: N/A

Cyanine 644-cAMP, 20x50 ug

00022-1-1 EA
EUR 647

Fluorescein Methotrexate, Triammonium Salt, 1 mg

00023 1MG
EUR 285
Description: N/A

Discordance between human sperm quality and telomere length following differential gradient separation/swim-up

Background: Strong evidence has suggested an important role of telomeres in meiosis, fertilization, and embryo development.
Purpose: To determine if sperm telomere length (STL) in sperm purified by differential gradient centrifugation followed by swim-up (selected STL) is correlated with sperm quality and clinical outcomes.
Methods: Relative selected STL was assessed by quantitative polymerase chain reaction (Q-PCR) in 78 consecutive assisted reproductive technology (ART) treatments during 2017. Statistical analyses were performed in the totality of patients, and in normozoospermic and non-normozoospermic patients. These included correlations between selected STL and sperm quality parameters, embryological parameters (multivariable linear regression), and clinical parameters (multivariable logistic regression).
Results: No significant correlations were found between selected STL and sperm quality in the total population. However, selected STL was significantly correlated with total sperm count (r = 0.361; P = 0.039) and sperm DNA fragmentation-post-acrosomal region pattern (r = – 0.464; P = 0.030) in normozoospermic patients. No relation was observed between selected STL and clinical outcomes in any clinical group.
Conclusions: As the correlations observed in normozoospermic patients were not representative of the whole heterogeneous population, differences in the sperm characteristics of the study population may lead to discrepant results when evaluating the association of STL with sperm quality. Since the total population selected STL was not related with sperm quality and with clinical outcomes, results do not support the use of selected STL measurement to evaluate the reproductive potential of the male patient or to predict the success rates of ART treatments.
Keywords: Assisted reproduction; Infertility biomarkers; Male infertility; Sperm telomere length

Dnalc4 antibody - middle region

MBS3210606-5x01mL 5x0.1mL
EUR 1995

Polyclonal Dnalc4 antibody - middle region

APR15793G 0.05mg
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Dnalc4 - middle region. This antibody is tested and proven to work in the following applications:

ARP52101_P050-25UL - Dnalc4 Antibody - middle region

ARP52101_P050-25UL 25ul
EUR 99

ARP52101_P050 - Dnalc4 antibody - middle region (ARP52101_P050)

ARP52101_P050 100ul
EUR 389

Dnalc4 (GFP-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4)

MG200362 10 µg Ask for price

Dnalc4 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4)

MR200362 10 µg Ask for price

Dnalc4 Peptide - middle region

MBS3235561-01mg 0.1mg
EUR 180

Dnalc4 Peptide - middle region

MBS3235561-5x01mg 5x0.1mg
EUR 730

Dnalc4 Recombinant Protein (Mouse)

RP129641 100 ug Ask for price

Dnalc4 ORF Vector (Mouse) (pORF)

ORF043215 1.0 ug DNA
EUR 607.2

Lenti ORF clone of Dnalc4 (mGFP-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4)

MR200362L4 10 µg Ask for price

Lenti ORF clone of Dnalc4 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4)

MR200362L3 10 µg Ask for price

Lenti ORF particles, Dnalc4 (GFP-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4), 200ul, >10^7 TU/mL

MR200362L4V 200 µl Ask for price

Dnalc4 sgRNA CRISPR Lentivector set (Mouse)

K4997501 3 x 1.0 ug
EUR 406.8

Dnalc4 3'UTR GFP Stable Cell Line

TU155288 1.0 ml Ask for price

Lenti ORF particles, Dnalc4 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4), 200ul, >10^7 TU/mL

MR200362L3V 200 µl Ask for price

Dnalc4 Protein Vector (Mouse) (pPM-C-HA)

PV172860 500 ng
EUR 723.6

Dnalc4 Protein Vector (Mouse) (pPB-C-His)

PV172858 500 ng
EUR 723.6

Dnalc4 Protein Vector (Mouse) (pPB-N-His)

PV172859 500 ng
EUR 723.6

Dnalc4 Protein Vector (Mouse) (pPM-C-His)

PV172861 500 ng
EUR 723.6

Dnalc4 3'UTR Luciferase Stable Cell Line

TU105288 1.0 ml Ask for price

Dnalc4 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4997502 1.0 ug DNA
EUR 184.8

Dnalc4 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4997503 1.0 ug DNA
EUR 184.8

Dnalc4 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4997504 1.0 ug DNA
EUR 184.8

Recombinant Mouse DNALC4 Protein, His (Fc)-Avi-tagged

DNALC4-2460M 50ug
EUR 2398.4
Description: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.

Dnal4 (untagged) - Mouse dynein, axonemal, light chain 4 (Dnalc4), (10ug)

MC200472 10 µg Ask for price

Dnalc4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4997505 3 x 1.0 ug
EUR 451.2

Dnalc4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4997506 1.0 ug DNA
EUR 200.4

Dnalc4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4997507 1.0 ug DNA
EUR 200.4

Dnalc4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4997508 1.0 ug DNA
EUR 200.4

Dnalc1 Antibody - C-terminal region

MBS3215526-01mL 0.1mL
EUR 455

Dnalc1 Antibody - C-terminal region

MBS3215526-5x01mL 5x0.1mL
EUR 1995

ARP62201_P050-25UL - Dnalc1 Antibody - C-terminal region

ARP62201_P050-25UL 25ul
EUR 99

ARP62201_P050 - Dnalc1 Antibody - C-terminal region (ARP62201_P050)

ARP62201_P050 100ul
EUR 389

Dnalc4 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL502994V 500 ul each Ask for price

Lenti ORF particles, Dnalc1 (GFP-tagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1), 200ul, >10^7 TU/mL

MR216479L4V 200 µl Ask for price

Dnalc1 (GFP-tagged) - Mouse dynein axonemal light chain 1 (Dnalc1), (10ug)

MG216479 10 µg Ask for price

Dnalc1 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1)

MR216479 10 µg Ask for price

Lenti ORF particles, Dnalc1 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1), 200ul, >10^7 TU/mL

MR216479L3V 200 µl Ask for price

Lenti ORF clone of Dnalc1 (mGFP-tagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1)

MR216479L4 10 µg Ask for price

Lenti ORF clone of Dnalc1 (Myc-DDK-tagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1)

MR216479L3 10 µg Ask for price

Dnalc1 ORF Vector (Mouse) (pORF)

ORF043214 1.0 ug DNA
EUR 607.2

Dnalc1 3'UTR GFP Stable Cell Line

TU155287 1.0 ml Ask for price

Dnalc1 Protein Vector (Mouse) (pPM-C-HA)

PV172856 500 ng
EUR 723.6

Dnalc1 Peptide - C-terminal region

MBS3240429-01mg 0.1mg
EUR 180

Dnalc1 Peptide - C-terminal region

MBS3240429-5x01mg 5x0.1mg
EUR 730

Dnalc1 Protein Vector (Mouse) (pPB-C-His)

PV172854 500 ng
EUR 723.6

Dnalc1 Protein Vector (Mouse) (pPB-N-His)

PV172855 500 ng
EUR 723.6

Dnalc1 Protein Vector (Mouse) (pPM-C-His)

PV172857 500 ng
EUR 723.6

Dnalc1 Recombinant Protein (Mouse)

RP129638 100 ug Ask for price

Dnalc1 3'UTR Luciferase Stable Cell Line

TU105287 1.0 ml Ask for price

Dnalc1 sgRNA CRISPR Lentivector set (Mouse)

K4077601 3 x 1.0 ug
EUR 406.8

Dnal1 (untagged) - Mouse dynein, axonemal, light chain 1 (Dnalc1), (10ug)

MC212110 10 µg Ask for price

Dnalc1 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4077602 1.0 ug DNA
EUR 184.8

Dnalc1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4077603 1.0 ug DNA
EUR 184.8

Dnalc1 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4077604 1.0 ug DNA
EUR 184.8

Recombinant Mouse DNALC1 Protein, His (Fc)-Avi-tagged

DNALC1-2459M 50ug
EUR 2398.4
Description: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.

Dnalc1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4077605 3 x 1.0 ug
EUR 451.2

Dnalc1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4077606 1.0 ug DNA
EUR 200.4

Dnalc1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4077607 1.0 ug DNA
EUR 200.4

Dnalc1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4077608 1.0 ug DNA
EUR 200.4

Dnalc1 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL505712V 500 ul each Ask for price

Somatostatin Analog D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-2-NaI-NH2

MBS659446-1mg 1mg
EUR 610

Somatostatin Analog D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-2-NaI-NH2

MBS659446-5x1mg 5x1mg
EUR 2600

Somatostatin Analog D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2.

MBS658360-1mg 1mg
EUR 610

Somatostatin Analog D-2-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2.

MBS658360-5x1mg 5x1mg
EUR 2600

Somatostatin Analog D-2-Nal-cyclo(-gamma-Glu-Tyr-D-Trp-Lys-Val-L-alpha, gamma-diaminobutyryl)-Thr-NH2

MBS633712-1mg 1mg
EUR 610

Somatostatin Analog D-2-Nal-cyclo(-gamma-Glu-Tyr-D-Trp-Lys-Val-L-alpha, gamma-diaminobutyryl)-Thr-NH2

MBS633712-5x1mg 5x1mg
EUR 2600

DNAL1 Antibody

8C15512 50ug
EUR 368
Description: DNAL1 Antibody

DNAL4 Antibody

8C15515 50ug
EUR 368
Description: DNAL4 Antibody

DNAL1 antibody

10R-10242 50 ul
EUR 216
Description: Mouse monoclonal DNAL1 antibody

DNAL1 Antibody

24729-100ul 100ul
EUR 468

DNAL1 Antibody

4733-002mg 0.02 mg
EUR 206.18
Description: DNAL1 Antibody: DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.

DNAL1 Antibody

4733-01mg 0.1 mg
EUR 523.7
Description: DNAL1 Antibody: DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.

DNAL4 Antibody

45946-100ul 100ul
EUR 302.4

DNAL4 Antibody

45946-50ul 50ul
EUR 224.4

DNAL1 Antibody

34660 100ul
EUR 319

DNAL1 Antibody

34660-100ul 100ul
EUR 302.4

DNAL1 Antibody

34660-50ul 50ul
EUR 224.4

DNAL1 Antibody

E034660 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DNAL1 Antibody

E11-15512C 100μg
EUR 225
Description: Available in various conjugation types.

DNAL4 Antibody

E11-15515C 100μg
EUR 225
Description: Available in various conjugation types.

DNAL4 Antibody

E10-30478A 100ul
EUR 225
Description: Available in various conjugation types.

DNAL4 Antibody

E10-30478P 100ul
EUR 225
Description: Available in various conjugation types.

DNAL4 Antibody

E10-30479A 100ul
EUR 225
Description: Available in various conjugation types.

DNAL4 Antibody

E10-30479P 100ul
EUR 225
Description: Available in various conjugation types.